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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
1998 3
2000 1
2001 3
2002 1
2003 1
2005 1
2006 3
2007 2
2008 2
2009 2
2015 2
2017 1
2022 1
2023 1
2024 0

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24 results

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Page 1
Integrated LC-MS/MS and network pharmacology approach for predictingactive ingredients and pharmacological mechanisms of Tribulus terrestris L. against cardiac diseases.
Vinay CM, Mehta CH, Bhat C, Kamath A, B Joshi M, Paul B, Nayak UY, Rai PS. Vinay CM, et al. J Biomol Struct Dyn. 2023;41(21):11930-11945. doi: 10.1080/07391102.2023.2199076. Epub 2023 Apr 12. J Biomol Struct Dyn. 2023. PMID: 37042962
Tribulus terrestris L. (Gokshura) is a medicinal herb used for treating cardiac diseases and several other diseases. However, the active ingredients and the possible mechanism of action for treating cardiac diseases remain unclear. ...Network pharmacology ana …
Tribulus terrestris L. (Gokshura) is a medicinal herb used for treating cardiac diseases and several other diseases. However, …
Theory and Applications of the (Cardio) Genomic Fabric Approach to Post-Ischemic and Hypoxia-Induced Heart Failure.
Iacobas DA, Xi L. Iacobas DA, et al. J Pers Med. 2022 Jul 29;12(8):1246. doi: 10.3390/jpm12081246. J Pers Med. 2022. PMID: 36013195 Free PMC article.
This report illustrates the theoretical bases and the mathematical framework of the GFP with applications to our microarray data from mouse models of post ischemic, and constant and intermittent hypoxia-induced heart failures. GFP analyses revealed the myocardium prioritie …
This report illustrates the theoretical bases and the mathematical framework of the GFP with applications to our microarray data from mouse …
Roles of alpha1A- and alpha1B-adrenoceptors in heart: insights from studies of genetically modified mice.
Woodcock EA. Woodcock EA. Clin Exp Pharmacol Physiol. 2007 Sep;34(9):884-8. doi: 10.1111/j.1440-1681.2007.04707.x. Clin Exp Pharmacol Physiol. 2007. PMID: 17645635 Review.
The phenotypes of the animals generated vary depending on whether the receptors are expressed specifically in heart or generally throughout the animal, but some overall conclusions can be drawn. 2. ...In contrast, alpha1A-AR cause substantially heightened contractility whe …
The phenotypes of the animals generated vary depending on whether the receptors are expressed specifically in heart or generally thro …
{alpha}1-Adrenergic receptor subtypes in nonfailing and failing human myocardium.
Jensen BC, Swigart PM, De Marco T, Hoopes C, Simpson PC. Jensen BC, et al. Circ Heart Fail. 2009 Nov;2(6):654-63. doi: 10.1161/CIRCHEARTFAILURE.108.846212. Epub 2009 Aug 6. Circ Heart Fail. 2009. PMID: 19919991 Free PMC article.
BACKGROUND: alpha1-adrenergic receptors (alpha1-ARs) play adaptive roles in the heart and protect against the development of heart failure. The 3 alpha1-AR subtypes, alpha1A, alpha1B, and alpha1D, have distinct physiological roles in mouse heart, but very lit …
BACKGROUND: alpha1-adrenergic receptors (alpha1-ARs) play adaptive roles in the heart and protect against the development of heart …
Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload.
O'Connell TD, Swigart PM, Rodrigo MC, Ishizaka S, Joho S, Turnbull L, Tecott LH, Baker AJ, Foster E, Grossman W, Simpson PC. O'Connell TD, et al. J Clin Invest. 2006 Apr;116(4):1005-15. doi: 10.1172/JCI22811. J Clin Invest. 2006. PMID: 16585965 Free PMC article.
An alpha1-adrenergic receptor (alpha1-AR) antagonist increased heart failure in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT), but it is unknown whether this adverse result was due to alpha1-AR inhibition or a nonspecific d …
An alpha1-adrenergic receptor (alpha1-AR) antagonist increased heart failure in the Antihypertensive and Lipid-Lowering Treatment to …
The PTIP-Associated Histone Methyltransferase Complex Prevents Stress-Induced Maladaptive Cardiac Remodeling.
Stein AB, Goonewardena SN, Jones TA, Prusick PJ, Bazzi AA, Belyavskaya JM, McCoskey MM, Dandar RA. Stein AB, et al. PLoS One. 2015 May 22;10(5):e0127839. doi: 10.1371/journal.pone.0127839. eCollection 2015. PLoS One. 2015. PMID: 26001054 Free PMC article.
PTIP deletion resulted in altered stress-induced gene expression profiles including blunted expression of ADRA1A, ADRA1B, JUN, ATP2A2, ATP1A2, SCN4B, and CACNA1G. These results suggest that H3K4 methylation patterns and the complexes that regulate them, specifically the PT …
PTIP deletion resulted in altered stress-induced gene expression profiles including blunted expression of ADRA1A, ADRA1B, JUN, ATP2A2 …
Cardiac 7-transmembrane-spanning domain receptor portfolios: diversify, diversify, diversify.
Liggett SB. Liggett SB. J Clin Invest. 2006 Apr;116(4):875-7. doi: 10.1172/JCI28234. J Clin Invest. 2006. PMID: 16585959 Free PMC article.
Enhanced signaling in myocytes by the G protein Gq has been implicated in cardiac hypertrophy and the transition to heart failure. alpha1-Adrenergic receptors (alpha1-ARs) are members of the 7-transmembrane-spanning domain (7-TM) receptor family and signal via interaction …
Enhanced signaling in myocytes by the G protein Gq has been implicated in cardiac hypertrophy and the transition to heart failure. al …
Electrical remodeling in a transgenic mouse model of alpha1B-adrenergic receptor overexpression.
Rivard K, Trépanier-Boulay V, Rindt H, Fiset C. Rivard K, et al. Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H704-18. doi: 10.1152/ajpheart.00337.2008. Epub 2008 Dec 26. Am J Physiol Heart Circ Physiol. 2009. PMID: 19112097 Free article.
Although alpha-adrenergic stimulation is thought to contribute to induction of arrhythmias in heart failure, the electrophysiological consequences of chronic alpha(1)-adrenergic activation have not been clearly defined. Thus we characterized ventricular repolarization and …
Although alpha-adrenergic stimulation is thought to contribute to induction of arrhythmias in heart failure, the electrophysiological …
Gene expression profiling of alpha(1b)-adrenergic receptor-induced cardiac hypertrophy by oligonucleotide arrays.
Yun J, Zuscik MJ, Gonzalez-Cabrera P, McCune DF, Ross SA, Gaivin R, Piascik MT, Perez DM. Yun J, et al. Cardiovasc Res. 2003 Feb;57(2):443-55. doi: 10.1016/s0008-6363(02)00696-x. Cardiovasc Res. 2003. PMID: 12566117
Cardiac hypertrophy induced by systemic overexpression of the alpha(1b)-AR in a mouse model does not progress to heart failure. We wanted to explore potential gene expression differences that characterize this type of hypertrophy that may identify genes that prevent progre …
Cardiac hypertrophy induced by systemic overexpression of the alpha(1b)-AR in a mouse model does not progress to heart failure. We wa …
Cardiovascular influences of alpha1b-adrenergic receptor defect in mice.
Vecchione C, Fratta L, Rizzoni D, Notte A, Poulet R, Porteri E, Frati G, Guelfi D, Trimarco V, Mulvany MJ, Agabiti-Rosei E, Trimarco B, Cotecchia S, Lembo G. Vecchione C, et al. Circulation. 2002 Apr 9;105(14):1700-7. doi: 10.1161/01.cir.0000012750.08480.55. Circulation. 2002. PMID: 11940550
24 results